Characterisation of an aptamer against the Runt domain of AML1 (RUNX1) by NMR and mutational analyses
نویسندگان
چکیده
منابع مشابه
Characterisation of an aptamer against the Runt domain of AML1 (RUNX1) by NMR and mutational analyses
Since the invention of systematic evolution of ligands by exponential enrichment, many short oligonucleotides (or aptamers) have been reported that can bind to a wide range of target molecules with high affinity and specificity. Previously, we reported an RNA aptamer that shows high affinity to the Runt domain (RD) of the AML1 protein, a transcription factor with roles in haematopoiesis and imm...
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ژورنال
عنوان ژورنال: FEBS Open Bio
سال: 2018
ISSN: 2211-5463
DOI: 10.1002/2211-5463.12368